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Explore the intricate world of chiral algebras and their connection to three-dimensional physics in this illuminating lecture by Sergei Gukov from the California Institute of Technology. Delve into the mathematical foundations and physical implications of chiral algebras, examining their emergence from three-dimensional systems and their significance in modern theoretical physics. Gain insights into cutting-edge research at the intersection of mathematics and physics, uncovering the deep relationships between algebraic structures and higher-dimensional theories.