Explore peroxisome structure and function in this 20-minute cell biology lecture. Learn about the normal functions of peroxisomes, including beta-oxidation of very long-chain fatty acids, alpha-oxidation of branched-chain fatty acids, ethanol metabolism, bile acid activation, cholesterol synthesis, plasmalogen synthesis, and catalase activity. Delve into USMLE Step 1 disorders related to peroxisomal deficiencies, focusing on Zellweger syndrome, Refsum's disease, and adrenoleukodystrophy. Gain a comprehensive understanding of these complex cellular processes and their associated disorders through clear explanations and detailed breakdowns of each topic.
Overview
Syllabus
- Overview
- VLCFA, BCFA, & Peroxisome's ABCD1 Transporters
- F1: Beta-Oxidation of VLCFA Pathway OHOT
- F2: Alpha-Oxidation of BCFA Pathway
- F3: Ethanol Metabolism
- F4: Bile Acid Activation & Metabolism
- F5: Cholesterol Synthesis
- F6: Plasmalogen Synthesis
- F7: Catalase Activity for Reducing H2O2 Buildup
- Zellweger Syndrome
- Refssum's Disease
- Adrenoleukodystrophy ALD
- Comment, Like, SUBSCRIBE!
Taught by
Ninja Nerd
