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Explore the structure and function of lysosomes in this comprehensive 33-minute lecture on cell biology. Delve into the normal function of lysosomes before examining lysosomal storage disorders in a USMLE Step 1 review. Learn about Tay-Sachs, Fabry, Gaucher, and Niemann-Pick Disease. Understand key concepts such as endocytosis, receptor-mediated endocytosis, and secondary lysosomes. Gain insights into the role of macrophages in these disorders. Perfect for medical students and those interested in cellular processes and genetic diseases.