Overview
Syllabus
Intro
Who is Dr Kuzak
Disclosure
Gail Model
Boadicea Model
IBIS Model
IBIS Version 8
Family History
First Degree Relatives
Reproductive Factors
Family Size Breastfeeding
Other Reproductive Factors
Other Hormones
Benign Breast Disease
Mammography Density
Breast Density
Tyrer Cuzick Model
Average Risk
Probability
The Model
The Family History
Relative Hazards
Density
Percent Density
Gareth Evans
Risk Assessment Questionnaire
Cohort
Results
Volumetric Data
By Rats
Risk Curves
Summary
Risk without density
Risk with density
Polygenic risk scores
Polygenic risk profiles
Procast cohort
More data
Future
Questions
Oral contraceptives
Oral contraceptives vs hormone replacement
Hormone replacement therapy
Risk due to benign disease
Risk due to lumpectomy
Risk due to another gene mutation
Gene testing
Next version
Two more questions
Is there more than masking
Thank you
Next lecture
Taught by
Ambry Genetics