Explore a 34-minute lecture on causal mapping of symptoms onto human brain circuits presented by Dr. Michael Fox from Brigham and Women's Hospital and Harvard Medical School. Delve into advanced neuroimaging techniques and their applications in localizing neuropsychiatric symptoms. Learn about lesion network mapping, depression lesion networks, and addiction remission targets. Discover how deep brain stimulation (DBS) and transcranial magnetic stimulation (TMS) network mapping contribute to understanding brain circuits. Examine convergent circuits for depression and epilepsy, and gain insights into the future of personalized brain circuit therapeutics. This BrainMap talk, hosted by the MGH Martinos Center, offers a comprehensive overview of cutting-edge research in mapping brain circuits and their relationship to neurological and psychiatric symptoms.
Overview
Syllabus
Causal Mapping of Symptoms onto Human Brain Circuits
How do we localize neuropsychiatric symptoms?
Correlates of Psychiatric Disease
Lesion Localization
The human brain connectome
Lesion "Network" Localization
Lesion Network Mapping
Lesion mapping of depression (n = 461)
Therapeutic relevance of depression lesion network
Addiction Remission Targets
Causal sources of Information
DBS Network Mapping
"Individualized" TMS Network Mapping
Symptom-Specific TMS Targets?
Convergent Depression Circuit
Convergent Epilepsy Circuit
Conclusions
Acknowledgements Collaborators
Center for BRAIN CIRCUIT THERAPEUTICS
Taught by
MGH Martinos Center
