Dive into a comprehensive 3-hour lecture on antiplatelet, anticoagulant, and thrombolytic agents. Explore the intricacies of platelet plug formation, coagulation cascade, and fibrinolysis. Learn about the mechanisms of action, indications, and adverse effects of various drugs used in managing neurological, cardiac, pulmonary, and vascular events. Understand venous thromboembolism prophylaxis and prevention of circuitry/catheter clotting. Delve into specific medications like aspirin, P2Y12 receptor blockers, PDE-3 inhibitors, heparin, direct-acting oral anticoagulants, and warfarin. Address critical topics such as bleeding risks, drug level monitoring, and reversal strategies. Conclude with practice problems to reinforce your understanding of these crucial pharmacological agents in medical practice.
Overview
Syllabus
Lab
Anticoagulants, Thrombolytics, Antiplatelets Introduction
Platelet Plug Formation
Coagulation Cascade
Fibrinolysis
Test Your Knowledge - Anticoagulants, Thrombolytics, Antiplatelets MOA
Neurological Events
Cardiac Events
Pulmonary Events
Peripheral & Central Vascular Events
Venous Thromboembolism Prophylaxis
Prevention of Circuitry/Catheter Clotting
Acetylsalicylic Acid Aspirin Adverse Effects
Aspirin Toxicity
P2Y12 Receptor Blockers Adverse Effects
PDE-3 Inhibitors Adverse Effects
Heparin UFH + LMWH Adverse Effects
Direct-Acting Oral Anticoagulants DOACs Adverse Effects
Warfarin Adverse Effects
Bleeding! Most Feared Adverse Effect
Drug Level Monitoring
Drug Reversal
Anticoagulants, Thrombolytics, Antiplatelets Practice Problems
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Taught by
Ninja Nerd
