Analysis of Bile Acid Composition in FGF19-Expressing Liver-Humanized Mouse Model for CYP3A4 Drug-Drug Interaction Studies

Explore a 25-minute webinar presented by Dr. Robert S. Jones, Principal Scientist at Genentech Inc., on the analysis of bile acid composition in a fibroblast growth factor 19-expressing liver-humanized mouse model and its application in CYP3A4-mediated drug-drug interaction studies. Delve into the challenges posed by the enlarged bile acid pool in liver-humanized mouse models and learn about potential solutions to improve the interpretation of results in drug metabolism and drug-drug interaction studies. Gain insights into translational in vitro models and in silico approaches for enhancing preclinical data translation to human applications. Earn PACE credits by watching the webinar and following the provided instructions. Connect with Labroots on various social media platforms for more scientific content and updates.