Amyotrophic Lateral Sclerosis - Understanding Upper and Lower Motor Neuron Lesions in Paralysis

Learn about Amyotrophic Lateral Sclerosis (ALS) in this 25-minute medical video that comprehensively covers the neurodegenerative condition also known as Lou Gehrig's disease. Explore the pathophysiology involving both Upper Motor Neuron Lesions (UMNL) and Lower Motor Neuron Lesions (LMNL), and understand how they affect the central and peripheral nervous systems. Master the clinical manifestations including spasticity, flaccid paralysis, spastic paresis, changes in deep tendon reflexes, muscle tone abnormalities, and characteristic signs like Babinski sign and clonus. Examine the progression of symptoms including respiratory paralysis, dysarthria, dysphagia, and loss of executive function, while understanding the differences between bulbar and pseudobulbar symptoms. Gain insights into the complex interplay between the corticospinal tract, corticobulbar tract, pyramidal tract, and extrapyramidal tract in this devastating motor neuron disease.