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Explore the intriguing phenomenon of chiral-induced spin selectivity (CISS) and its implications for time-reversal symmetry breaking in this comprehensive lecture. Delve into the recent experimental discoveries showing how electrons scattered by helical organic molecules become spin-polarized, and examine the ongoing debate surrounding the theoretical explanation of this effect. Investigate various models and approaches to overcome Bardarson's theorem, including leakage from molecular ions, additional terminals, magnetic fields, time-dependent potentials, and non-linear effects. Analyze the tight-binding Hamiltonian model with Rashba spin-orbit interactions along the helix and additional hopping in the direction of the helix axis. Critically evaluate recent alternative theories and gain insights into the complexities of CISS, highlighting the current state of research in this fascinating field of physics.