Advancing Gene Editing Technologies with Spherical Nucleic Acids

Explore a 41-minute webinar presented by Dr. Sergej Kudruk, an IIN Postdoctoral Fellow at Northwestern University, on advancing gene editing technologies using Spherical Nucleic Acids (SNAs). Delve into the pivotal role of nanomaterials in overcoming limitations of traditional drugs, with a focus on SNAs as a versatile class of nanomaterials used in diagnostics and therapeutics. Learn about the unique advantages of SNAs, comprised of nanoparticle cores densely functionalized with radially oriented oligonucleotides, and their superior properties compared to linear nucleic acids. Gain insights into Dr. Kudruk's research interests spanning chemistry, biology, and biomaterials, with emphasis on developing therapeutics for cancer and neurodegenerative diseases. Discover methods for precision delivery of hydrophilic and amphiphilic cargo into mammalian cells, as explored during Dr. Kudruk's doctoral studies.