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Acute Intermittent Porphyria - Disorders of Heme Synthesis - Biochemistry & Hematology

Medicosis Perfectionalis via YouTube

Overview

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Explore the intricacies of Acute Intermittent Porphyria (AIP) in this comprehensive 22-minute video on disorders of heme synthesis. Delve into the genetic basis of AIP, focusing on the deficiency of porphobilinogen deaminase enzyme in the heme metabolism pathway. Learn about the characteristic symptoms, including severe abdominal pain, neuropsychiatric manifestations, and peripheral neuropathy. Understand the unique presentation of purple-colored urine and elevated levels of porphobilinogen, aminolevulenic acid, and porphyrins. Discover treatment options such as glucose and hemin administration. Compare and contrast AIP with other types of porphyria, particularly porphyria cutanea tarda, to gain a comprehensive understanding of these hematological disorders.

Syllabus

Acute Intermittent Porphyria | Disorders of Heme Synthesis | Biochemistry & Hematology

Taught by

Medicosis Perfectionalis

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