Accurately Modeling Mild Traumatic Brain Injury to Better Understand Function Mechanisms

Explore the latest research on mild traumatic brain injury (mTBI) modeling in this 33-minute webinar presented by Dr. Brian Christie. Learn about the awake closed-head injury (ACHI) model, an ecologically valid approach for studying mTBI in preclinical settings. Discover how this technique produces clinically relevant behavioral deficits in rodents without craniotomy or anesthesia, making it ideal for investigating repetitive mTBI. Gain insights into the distributed brain injury associated with ACHI, including microbleeds, microglia activation, and synaptic pruning. Understand the impact on synaptic plasticity and its implications for learning and memory processes. Delve into ongoing research on synaptic plasticity deficits and the long-term effects of early-life mTBI on the aging brain. Earn PACE credits by watching the webinar and following the provided instructions.