Overview
Discover a groundbreaking approach to preventing mitochondrial disease in this 15-minute TED talk by University of Newcastle professor Mary Herbert. Learn about the challenges faced by parents with inheritable genetic conditions, particularly those with mutated mitochondrial DNA (mtDNA). Explore the innovative solution Herbert presents to ensure that affected mtDNA mutations are not passed on to future generations. Delve into the complexities of DNA, mitochondrial DNA, and the devastating effects of mitochondrial diseases. Follow Herbert's journey as she pushes the boundaries of reproductive science, overcoming setbacks and developing modified procedures like three-parent IVF. Gain insight into the potential impact of these treatments and the ultimate goal of eliminating certain mitochondrial diseases from families for generations to come.
Syllabus
Intro
What is DNA
What is mitochondrial DNA
Women who carry mitochondrial disease
How can we help
Challenges
What can be done
Proof of concept
First setbacks
Changing the timing
Modified procedure
Three parent IVF
What do these treatments mean
Our goal
Taught by
TEDMED