Solvation, Hydrogen-Bonding, and Ionophores in Organic Chemistry - Lecture 5

Explore the fundamental concepts of solvation, hydrogen bonding, and ionophores in this 47-minute lecture from Yale University's Freshman Organic Chemistry II course. Delve into the importance of non-bonded interactions in organic reactions, particularly for ions in solution. Examine how these interactions, including hydrogen bonding, influence physical properties such as boiling points. Understand the principles of electrostatics and polarizability in relation to non-bonded interactions. Investigate the role of artificial and natural ion carriers (ionophores) in binding specific ions. Learn about the energetics of water's ionic dissociation in the gas phase. The lecture covers various topics, including alcohol oxidation mechanisms, solvophobic forces, phase-transfer catalysis, and gas-phase heterolysis energetics, providing a comprehensive overview of these essential organic chemistry concepts.