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XuetangX

Craniofacial and Oral Genetic Diseases

via XuetangX

Overview

Craniofacial and oral cavity are essential parts of the body, contributing significantly to overall health and well-being. Nearly one-third of human genetic diseases present more or less abnormalities in craniofacial and oral areas. Malformations in these regions affect the structure and appearance as well as various physiological functions, which impose a heavy burden on the patients and society. 

Most of craniofacial and oral genetic diseases have lower prevalence and complicated phenotypes, and many dentists have little knowledge about diagnosis and treatment of such diseases. 

In order to conduct a professional training and reach a worldwide consensus on craniofacial and oral genetic diseases, professor Xiaohong Duan and her team from Air Force Medical University launches this case-based course. Professor Duan built the first domestic clinic of oral rare diseases and genetic diseases, wrote the first text book about Oral Genetics in Chinese, opened the course for undergraduate and graduated students, organized Society of Oral Genetic Diseases and Rare Diseases, Chinese Stomatological Association as the founding chairman.  Professor Duan and her team have accumulated many rare and precious clinical data of oral genetic diseases.

This course consists of three chapters with 19 sections, covering 12 kinds of representative diseases. Through the case based learning chain, you would get an overview and basic knowledge about craniofacial and oral genetic diseases, and understand the diagnostic criteria, complex pathogenic mechanism and genetics background as well as the treatment strategies of these diseases.

Syllabus

  • Part One:General Introduction
    • Craniofacial and oral genetic diseases
    • Diagnosis and treatment of oral genetic diseases
  • Part Two:Craniofacial and Oral Genetic Diseases
    • Amelogenesis Imperfecta
    • Case analysis of amelogenesis imperfecta with AMELX mutations
    • Hereditary dentin defects
    • Dentin defects with rickets
    • Dentin dysplysia type I
    • Case analysis of supernumerary teeth
    • A multiple idiopathic cervical root resorption case report
    • Pedigree study of MSX1 mutation lead to selective tooth agenesis type I
    • Selective tooth agenesis caused by PAX9 gene mutations
    • Case analysis of tooth agenesis and dentin dysplasia with SMOC2 mutation
    • Selective failure of tooth eruption(SFTE)
    • Cherubism
  • Part Three:Craniofacial and Oral Genetic Diseases with Systemic Diseases
    • Hypercementosis with pycnodysostosis
    • Papillon-Lefèvre Syndrome
    • Craniofacial and oral features with osteopetrosis
    • Case Analysis of Peutz‑Jeghers Syndrome with STK11 Mutation
    • EEC Syndrome (Ectrodactyly-Ectodermal dysplasia-Cleft lip/palate Syndrome)
  • Final Exam

    Taught by

    Air Force Medical University(AFMU)

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