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XuetangX

医学数据挖掘

via XuetangX

Overview

Learn essential medical data mining techniques through a comprehensive course covering linear and non-linear regression models, Meta-analysis, predictive model evaluation, dimensionality reduction methods, classification models, and deep learning applications in healthcare. Master data preprocessing, various regression analyses including Logistic and Cox survival analysis, dose-response modeling, ROC analysis, clustering techniques, and advanced classification methods like K-nearest neighbors, Support Vector Machines, and Random Forests. Explore practical applications in clinical diagnostics, mRNA microarray classification, miRNA marker extraction, and deep learning implementations using CNN for genomics and RNN for time series analysis. Develop expertise in applying these statistical and machine learning methods to real medical data through hands-on practice and culminating in a final examination.

Syllabus

  • 第一讲:线性回归预测模型
    • 1.1 数据预处理
    • 1.2.1 一元线性回归分析
    • 1.2.2 多元线性回归分析
  • 第二讲:非线性回归预测模型
    • 2.1 Logistic回归分析
    • 2.2 非线性回归分析
    • 2.3 偏最小二乘回归分析
    • 2.4 倾向性得分匹配方法
    • 2.5 Cox生存分析
  • 第三讲:Meta分析
    • 3.1 Meta分析
    • 3.2 剂量-反应模型Meta分析
  • 第四讲:预测模型评价
    • 4.1 ROC分析
    • 4.2 两组ROC曲线下的面积比较
    • 4.3 C-statistics、C-index分析
  • 第五讲:数据降维方法
    • 5.1 主成分分析
    • 5.2因子分析
    • 5.3 聚类分析
    • 5.4 基于聚类分析的临床诊断模型
  • 第六讲:数据分类模型
    • 6.1 K近邻模型
    • 6.2 支持向量机模型及应用
    • 6.3 基于支持向量机的mRNA微阵列数据分类
    • 6.4 决策树模型及应用
    • 6.5基于决策树的临床诊断模型
    • 6.6 随机森林模型
    • 6.7 基于随机森林的miRNA标志物提取
    • 6.8 判别分析
    • 6.9 关联分析
    • 6.10 贝叶斯网络分析
  • 第七讲:深度学习
    • 7.1 感知机模型
    • 7.2 CNN在图像深度学习中的应用
    • 7.3CNN在基因组学中的应用
    • 7.4 RNN在时间序列深度学习中的应用
  • 期末考试

    Taught by

    Hubei University of Medicine

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