ABOUT THE COURSE: The course addresses the approach of how to develop the portable, reusable, robust, ultrasensitive and efficient point-of-care (POC) systems that has received significant attention in the healthcare system and analytical process and explains the science behind the detection of analyte of interest at the early stage of diagnosis. Students also will learn the techniques of commercialization of diagnostic devices.INTENDED AUDIENCE: UG-PG, RS Students, Faculty Members, Industry Professionals, and Medical Professionals.PREREQUISITES: 10+2 (only basic Sciences)INDUSTRY SUPPORT: 1) Coromandel International Limited 2) PalmSens 3) Zensor 4) GE Healthcare 5) Greyfalcon Healthcare Private Limited 6) Metrohm
Nanobio Technology Enabled Point-of-Care Devices
Indian Institute of Technology, Kharagpur and NPTEL via Swayam
Overview
Syllabus
Week 1: Introduction and basic concept of point-of-care diagnosis,Analytical Chemistry with Biological applications and their mechanistic studies in diagnosis: thermodynamics,chemical kinetics, rate constant.Week 2:Nanobiomaterials: fundamental concept. Nanomaterials for early stage biomarker detection, synthesis and characterization of Nanoparticles and their use for Biosensors and Biodevices, Biofunctionalization of nanomaterials, beneficial properties of nanomaterials for diagnosis.Week 3:Basic tools used in diagnostics, Signal amplification chemistry for higher signal-to-background ratios: Redox Cycling amplification methods, electrode surface modification with nanomaterials.Week 4:Lab-on-a-chip devices for biomedical diagnostics, Multiplex diagnostic microsystem development for rapid quantification, Non-Invasive approach, Printed bioelectronics.Week 5:New detection systems for POCT and integration of highly sensitive Biosensors to mobile devices: Wash-free detection, label-free detection, Lab-on-Printed circuit board.Week 6:New detection systems for POCT and integration of highly sensitive Biosensors to mobile devices: Wearable biosensors, smart phone-based platform, disposable self- powered POCT Devices.Week 7:Device characterization and challenges.Week 8:Commercialization of biosensor and biodevices,environmental field monitoring, food safety, and security.
Taught by
Prof. Gorachand Dutta
