ABOUT THE COURSE :Several branches of engineering involve the study of the nervous system. Engineering students of various branches are expected to understand the nervous system and perform neural surgical experiments on animal models. Rodent being the most common animal model used in the field of bioscience modules, it is important to know how to perform the surgical experiments themselves. The module is designed for students to understand the functioning of the nervous system without a detailed understanding of biology. Further, the students will be exposed to engineering opportunities in developing technologies for understanding the functioning of the nervous system.INTENDED AUDIENCE : Engineering Students, Faculty from Engineering Colleges, Medical Students, Faculty from Medical Colleges.PREREQUISITES : Preferable, but not essential, to have taken the NPTEL Sensors and Actuators.INDUSTRY SUPPORT : MathWorks, Open BCI, Medtronic DBS systems, Neuroprosthetic device industries.
Microsensors, Implantable Devices and Rodent Surgeries for Biomedical Applications
NPTEL and Indian Institute of Science Bangalore via Swayam
Overview
Syllabus
Week 1 :Logistics in rodent experiments: Personal Protective Equipment, Procurement and quarantine of laboratory animals, Husbandry and Handling of rodents, Breeding and Care of Rats and Mice.
Week 2 :Rodents for Neural experiments: Species of rodents used in neural experiments, Rodent identification, and selection for experiments
Week 3:Rodent Neural Sensors and Data acquisition systems, Epileptic Seizure Detection and Classification
Week 4 :Microbial and Health monitoring for chronic neural experiments.
Week 5 :Neural system models in rodents – Epilepsy, Stroke, Motor movements, Parkinsonian models and application of rodent neural experiments, Microfabrication for neural engineering, PVD, CVD, Lithography, Etching
Week 6 :Behavioral setups for neural experiments, Different Brain-Computer Interfaces, Micro Electrode Array
Week 7 :Rodent Micro Neurosurgery I: Rodent anesthesia techniques, Introduction, Neuroanatomy – Applied and Comparative (rodent /monkey/ human) Equipments, Sterility and sterilization, Craniotomy, Microneurosurgical instruments and techniques, Sensor implantation and head mounting techniques, Closure techniques and challenges, Implant care for chronic recordings
Week 8 :Rodent Micro Neurosurgery II: Spinal anatomy, Spinal cord sensors and implantation surgeries, Peripheral neural anatomy, Peripheral neural surgeries, Peripheral neural sensors, and implantation, Different neural experiments as an example, Recovery process, Biological Basis of Contemporary Neural Networks and Neural Substrates for Contemporary Neural Networks
Week 9 :Rodent neuropathology: Euthanasia and Brain harvesting techniques. Neuropathological processing of the harvested brain, Electronic System Development for neural experiments
Week 10 :Challenges in neural signals and synchronization of behaviors, Brain Stimulation: Introduction and Applications, Experimental Protocol for Neural Experiments
Week 11 :Neural signal processing and post-processing, EEGLAB, ERPLAB, Event-Related Potentials: Introduction and Applications, ERP Extraction, Time-Frequency Analysis, Signal Interpretation
Week 12 :Decoding techniques and challenges, Recent Trends in Neural Engineering
Week 2 :Rodents for Neural experiments: Species of rodents used in neural experiments, Rodent identification, and selection for experiments
Week 3:Rodent Neural Sensors and Data acquisition systems, Epileptic Seizure Detection and Classification
Week 4 :Microbial and Health monitoring for chronic neural experiments.
Week 5 :Neural system models in rodents – Epilepsy, Stroke, Motor movements, Parkinsonian models and application of rodent neural experiments, Microfabrication for neural engineering, PVD, CVD, Lithography, Etching
Week 6 :Behavioral setups for neural experiments, Different Brain-Computer Interfaces, Micro Electrode Array
Week 7 :Rodent Micro Neurosurgery I: Rodent anesthesia techniques, Introduction, Neuroanatomy – Applied and Comparative (rodent /monkey/ human) Equipments, Sterility and sterilization, Craniotomy, Microneurosurgical instruments and techniques, Sensor implantation and head mounting techniques, Closure techniques and challenges, Implant care for chronic recordings
Week 8 :Rodent Micro Neurosurgery II: Spinal anatomy, Spinal cord sensors and implantation surgeries, Peripheral neural anatomy, Peripheral neural surgeries, Peripheral neural sensors, and implantation, Different neural experiments as an example, Recovery process, Biological Basis of Contemporary Neural Networks and Neural Substrates for Contemporary Neural Networks
Week 9 :Rodent neuropathology: Euthanasia and Brain harvesting techniques. Neuropathological processing of the harvested brain, Electronic System Development for neural experiments
Week 10 :Challenges in neural signals and synchronization of behaviors, Brain Stimulation: Introduction and Applications, Experimental Protocol for Neural Experiments
Week 11 :Neural signal processing and post-processing, EEGLAB, ERPLAB, Event-Related Potentials: Introduction and Applications, ERP Extraction, Time-Frequency Analysis, Signal Interpretation
Week 12 :Decoding techniques and challenges, Recent Trends in Neural Engineering
Taught by
Prof. Hardik Jeetendra Pandya, Prof. Shabari Girishan K V
