The study of human genetics can be intellectually fascinating, but it also has plenty of practical applications. From the use of DNA in court cases to the discovery of new therapies for genetic diseases, a thorough understanding of the human genome can have important medical, social and legal impacts. Understanding the genetic basis behind human disease is one of the most important reasons for studying the human genome. While many genetic disorders are not treatable, early diagnosis can help improve the quality of life or even extend the lifespan of sufferers.Current clinical trials on genetic therapies offer the promise of eventual treatments that may give sufferers a life free of symptoms. Diagnostic tests can help couples decide whether to risk passing on specific disease-related genes to their children. Tests assist in vitro fertility doctors to specifically select embryos that do not carry the dangerous gene.
Overview
Syllabus
Day
Weekly Lecture Topics
TITLE OF VIDEO LECTURE AND READING TEXT
Week 1
Episode 1
1 Introduction
Episode 2
2 Dermatoglyphics 1
Episode 3
3 Dermatoglyphics 2
Week 2
Episode 4
4. Pedigree analysis 1
Episode 5
5. Pedigree Analysis 2
Episode 6
6 Chromosomes
Week 3
Episode 7
7. Heterochromatin
Episode 8
8. Ultrastructure of Chromosome
Episode 9
9. Human Karyotype
Episode 10
10 Banding techniques
Week 4
Episode 11
11. Euploidy and monoploidy
Episode 12
12. Haploidy and polyploidy
Episode 13
13. Anueploidy and nondisjunction
Episode 14
14. Deletions with examples
Week 5
Episode 15
15. Duplications with examples
Episode 16
16. Inversions with examples
Episode 17
17. Translocations with examples
Episode 18
18. Evolutionary significance of Chromosomal aberrations
Week 6
Episode 19
21 Genetic disease and inheritance pattern
Episode 20
22.a)Autosomal dominant inheritance
Episode 21
22.b)Autosomal recessive inheritance
Week 7
Episode 22
23. X- and Y-linked inheritance
Episode 23
24. Multifactorial & mito diseases
Episode 24
25. Oncogenetics
Week 8
Episode 25
26.Tumour suppressor genes
Episode 26
27.Cells of immune system
Episode 27
28. Genetics of immune system
Week 9
Episode 28
29. Innate adaptive immunity & I response
Episode 29
30. Inherited Immunodeficiency
Episode 30
31.a) HGPs i.e. Human Genome Projects
Episode 31
31.b) HGPs i.e. Human Genome Projects
Week 10
Episode 32
32.Genetic markers-SNPs and applications
Episode 33
33. Genetic markers-CNVs and InDels and their implications
Episode 34
34. Prenatal diagnosis- Non-invasive methods
Episode 35
35. Prenatal diagnosis- Invasive method
Week 11
Episode 36
36. Technology in reproductive assistance
Episode 37
37. Gene therapy with reference to hemophilia
Episode 38
38.Cord blood banking and stem cell therapy
Week 12
Episode 39
39.Genetic counseling
Episode 40
40. Eugenics- positive and negative implications
Taught by
Prof. N. B. Ramachandra
