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Taipei Medical University

Pharmacokinetics: Drug Dosing in Renal Disease

Taipei Medical University via FutureLearn

Overview

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Learn how renal disease affects kidney function and how to apply dosing regimens

On this course, you will learn the principles of pharmacokinetics and drug dose adjustment in patients with renal disease. You will be introduced to basic kidney physiology and functions, including the filtration, secretion and reabsorption of water, and the mechanisms of renal drug excretion.

You will learn how to calculate renal clearance, and how to recommend dosing regimen for patients with the disease. You will also explore the general principles for dosage adjustment in dialysis patients, and be able to describe the typical clinical presentation of chronic renal failure.

This course is for anyone requiring clinical pharmacokinetic knowledge, including undergraduate pharmacy students, post-graduate pharmacy students and pharmacists in clinical practice.

Syllabus

  • Renal Excretion in ESRD
    • Welcome to the Course
    • Evaluation of Renal function
    • Reflection and Assessment of the week
  • Dosing Regimen and TDM in Renal Failure
    • Effects of renal failure & TDM
    • Reflection and Assessment of the week
  • General cases for patients with renal failure
    • Clinical pharmacotherapy in renal failure
    • General Questions
    • Reflection and Assessment of the week
  • Dosing Regimen in Renal Dialysis
    • Hemodialysis and Peritoneal dialysis
    • Reflection and Assessment of the week
  • A closer look at Acute Renal Failure
    • Clinical considerations for patients in acute renal failure
    • Reflection and Assessment of the week
  • An overview of Chronic Kidney Disease
    • Chronic Kidney Disease : Diagnosis, complications, and the treatment
    • Reflection and Assessment of the week
    • Assessment Time

Taught by

Shawn Chen

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