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This comprehensive course provides a deep dive into Express.js, a robust web application framework for Node.js. Participants will master fundamental concepts, architecture, and the step-by-step process of setting up Express.js projects. Explore HTTP methods, route definition, and parameter extraction, gaining practical skills in setting up requests with Thunder Client and Postman tools. Delve into middleware's pivotal role, crafting custom functions and distinguishing built-in from custom middleware. Navigate error handling with proficiency in addressing synchronous errors and transmitting appropriate responses. The course extends to integrating MongoDB with Express.js, covering CRUD operations. Concluding with user authentication, participants acquire skills in generating and managing JWTs for secure authentication practices.