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Understanding File Formats in Bioinformatics - VCF and gVCF
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- 1 Intro
- 2 What is a VCF file and how is it generated?
- 3 Main sections of a VCF file
- 4 Metadata section
- 5 Header line
- 6 Data lines - description of fields
- 7 Genes and alleles
- 8 Understanding genotype
- 9 What does genotype 2/0 or 1/2 mean?
- 10 Difference between GT:0/1 and GT:0|1 - phased vs unphased genotype
- 11 How are variants recorded in a VCF file?
- 12 Interpreting a record in VCF
- 13 Genomic VCF gVCF