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Disordered protein systems
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Small-Molecule Binding to Intrinsically Disordered Proteins - Characterization and Implications for Drug Design
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- 1 Intro
- 2 Introducing disordered proteins
- 3 Disordered protein systems
- 4 Nuclear Magnetic Resonance Spectroscopy (NMR)
- 5 All-atom molecular dynamic simulations
- 6 Conformational entropy of the protein
- 7 Conformational entropy: 'entropic expansion
- 8 Limitations of simulations
- 9 Dynamics of 10074-G5 binding
