Evolution of Gene Regulation Following Whole Genome Duplication in Salmonids

Evolution of Gene Regulation Following Whole Genome Duplication in Salmonids

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The OU-model: A framework to model expression evolution

12 of 25

12 of 25

The OU-model: A framework to model expression evolution

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Evolution of Gene Regulation Following Whole Genome Duplication in Salmonids

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  1. 1 Intro
  2. 2 Who are the salmonids ?
  3. 3 The Atlantic salmon Culture and cash
  4. 4 Salmonids a model for genome evolution after WGD
  5. 5 Salmonid genomes 101
  6. 6 Gene loss/retention after Ss4R
  7. 7 Tissue regulatory divergence
  8. 8 How does gene regulation diverge?
  9. 9 Mode of tissue regulation divergence
  10. 10 Assymetric divergence following ancient vertebrate WGDs
  11. 11 A challenge... distinguishing between evolutionary scenarios
  12. 12 The OU-model: A framework to model expression evolution
  13. 13 The experiment
  14. 14 Tests for expression level shift
  15. 15 Tissue specific evolution?
  16. 16 Signatures of ongoing pseudogenization ?
  17. 17 Are particular cellular functions
  18. 18 Brief summary 2: expression evolution following WGD
  19. 19 Approach: ATAC-seq&TFBS footprinting
  20. 20 Sanity check = OK
  21. 21 Cis-regulatory evolution and tissue specificity
  22. 22 Does Tes contribute to novel 'adaptive' expression phenotypes?
  23. 23 Brief summary 3: CREs and duplicate expression evolution
  24. 24 Some concluding thoughts
  25. 25 Acknowledgements

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