Research Seminar - Identifiability and Inference in Cell Biology

Research Seminar - Identifiability and Inference in Cell Biology

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Drosophila egg chamber

5 of 26

5 of 26

Drosophila egg chamber

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Classroom Contents

Research Seminar - Identifiability and Inference in Cell Biology

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  1. 1 Intro
  2. 2 Research focus
  3. 3 Challenges of quantitative data
  4. 4 The inverse problem
  5. 5 Drosophila egg chamber
  6. 6 Compartment-based model
  7. 7 Typical behaviour of the solution
  8. 8 Parameter inference
  9. 9 RNA complex assembly
  10. 10 Quasi-steady distribution
  11. 11 Transport strongly biased
  12. 12 Dynamic regime
  13. 13 Over-expression mutant
  14. 14 Model predictions
  15. 15 Robustness of accumulation
  16. 16 Other mechanisms at play? . Could be a range of mechanisms at play that engender robustness to the system
  17. 17 Model comparison
  18. 18 Experimental data
  19. 19 Model building and identifiability
  20. 20 Mathematical models
  21. 21 Identifiability analysis Approach
  22. 22 MCMC results - Model 1
  23. 23 Profile likelihood analysis
  24. 24 Take-home message
  25. 25 Summary
  26. 26 Acknowledgements

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