Protein Evolution and Structure - Lecture 1

Protein Evolution and Structure - Lecture 1

International Centre for Theoretical Sciences via YouTube Direct link

How to evaluate the functional effect of mutation?

13 of 16

13 of 16

How to evaluate the functional effect of mutation?

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Protein Evolution and Structure - Lecture 1

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  1. 1 Start
  2. 2 Central Dogma: DNA to RNA to Protein
  3. 3 Amino acid structure
  4. 4 Aliphatic and hydrophobic side chains
  5. 5 Definitions of
  6. 6 Antiparallel B-sheet
  7. 7 Energy and forces
  8. 8 Hydrophobic effect
  9. 9 Haemoglobin: carries oxygen from the respiratory organs to the rest of the body.
  10. 10 X-ray crystallography simplified
  11. 11 NMR spectroscopy of proteins protein-lecture googl...
  12. 12 NMR and protein dynamics
  13. 13 How to evaluate the functional effect of mutation?
  14. 14 What information is stored in sequences?
  15. 15 Transplanting a unique allosteric effect from crocodile into human haemoglobin
  16. 16 How to extract useful information from protein sequences?

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