Probing Principles of Genome Organization and Function

Probing Principles of Genome Organization and Function

Center for Physical Genomics and Engineering via YouTube Direct link

Monthly Seminar on Physical Genomics

1 of 12

1 of 12

Monthly Seminar on Physical Genomics

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Probing Principles of Genome Organization and Function

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  1. 1 Monthly Seminar on Physical Genomics
  2. 2 Probing principles of genome organization and function
  3. 3 How do Enhancers select their target Promoter
  4. 4 Combinatorial EP reporter assay
  5. 5 Testing for selectivity
  6. 6 Does compatibility make enhancers and promoter loop more frequently?
  7. 7 How does location of genes and regulatory elements affect function?
  8. 8 Scalable "hopping" of DNA elements
  9. 9 Sox2 gene forms a strong barrier for activation by SCP
  10. 10 Does loop extrusion start from the SCR, proceed to the left catch the first gene it encounters?
  11. 11 Lamina associated domains (LADs)
  12. 12 A more scalable strategy?

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