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Determinants of pain
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Classroom Contents
Postoperative Evidence Based Analgesia - Fact or Fiction?
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- 1 Intro
- 2 Determinants of pain
- 3 Level of research
- 4 Fundamental questions around opioids and drug trials Measurement of plasma morphine levels
- 5 Hormonal and metabolic stress responses after major surgery in children aged 0-3 years: a double-blind, randomized trial comparing the effects of continuous versus intermittent morphine
- 6 Pharmacodynamics
- 7 Randomised Controlled Trial evaluating the effect of additional paracetamol during morphine infusion
- 8 Validation of the proposed dosing regimen in a prospective trial (NTR1438)
- 9 Pediatric Anesthesia
- 10 Conclusions
