Deep Learning for Genomic Discovery

Deep Learning for Genomic Discovery

Broad Institute via YouTube Direct link

Bias corrected profiles

14 of 25

14 of 25

Bias corrected profiles

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Classroom Contents

Deep Learning for Genomic Discovery

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  1. 1 Introduction
  2. 2 Presentation
  3. 3 high resolution assays
  4. 4 footprint shapes
  5. 5 single base pair resolution
  6. 6 total counts
  7. 7 interpretation
  8. 8 linear mapping
  9. 9 additive decomposition
  10. 10 modisco
  11. 11 how it works
  12. 12 using bodisco
  13. 13 TN5 Bias
  14. 14 Bias corrected profiles
  15. 15 Bias correction with neural network
  16. 16 Bias correction in two ways
  17. 17 Bias correction in actual genomes
  18. 18 Bias correction genomewide
  19. 19 Deep left profiles
  20. 20 Motif discovery
  21. 21 Summary
  22. 22 Discussion session
  23. 23 Highlights
  24. 24 Variant effect score
  25. 25 Bias Factorization

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