Learning Representations for Image-Based Profiling of Perturbations - MPG Primer 2023

Learning Representations for Image-Based Profiling of Perturbations - MPG Primer 2023

Broad Institute via YouTube Direct link

Combined Cell Painting dataset

15 of 20

15 of 20

Combined Cell Painting dataset

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Learning Representations for Image-Based Profiling of Perturbations - MPG Primer 2023

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  1. 1 Intro
  2. 2 Cell Painting assay
  3. 3 Image-based morphology profiling: introduction
  4. 4 Predicting assay-compound interaction
  5. 5 Predicting cell health phenotypes
  6. 6 Lung cancer variant impact prediction
  7. 7 Sources of features
  8. 8 Profiling cell state: classical features
  9. 9 Transfer learning: pre-trained CNNs
  10. 10 Weakly supervised learning (WSL)
  11. 11 Confounders for WSL
  12. 12 Single-cell classification results
  13. 13 Batch-correction with sphering
  14. 14 Perturbation selection
  15. 15 Combined Cell Painting dataset
  16. 16 Cell Painting CNN-1 training
  17. 17 Cell Painting CNN-1 performance
  18. 18 Effect of batch correction
  19. 19 Cell Painting CNN-1 qualitative analysis
  20. 20 Cell Painting CNN-1 availability

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