Molecular Epidemiology - Critical Applications in Public Health and Clinical Laboratories

Molecular Epidemiology - Critical Applications in Public Health and Clinical Laboratories

American Society for Microbiology via YouTube Direct link

Molecular Epidemiology Fellowship (MEF)

20 of 20

20 of 20

Molecular Epidemiology Fellowship (MEF)

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Molecular Epidemiology - Critical Applications in Public Health and Clinical Laboratories

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  1. 1 Intro
  2. 2 A brief history of molecular typing techniques.
  3. 3 Characteristics of molecular typing methods.
  4. 4 Pulsed-Field Gel Electrophoresis (PFGE)
  5. 5 PHL NGS Capacity in the United States (2013-2018)
  6. 6 Foodborne illness: From Patient to Public Health Surveillance
  7. 7 Transition to Use of Whole Genome Sequencing in PulseNet
  8. 8 Using WGS to Link Clinical Cases with Outbreak Source
  9. 9 Potential Importance of REPs in Reducing Disease Incidence . Most illnesses reported through PulseNet are not linked to a source - 10% of isolates are part of an outbreak
  10. 10 Investigating REP Strains • Repeated/ongoing identification of the same strain suggests that there is an upstream contributor or reservoir - Traditional outbreak control measures, like product recall…
  11. 11 CgMLST Minimum Spanning Tree of REPEXHO2 Strain by Outbreak (n=398 Human and Environmental Isolates)
  12. 12 Candida auris: Urgent AR Threat
  13. 13 Distinct C. auris strains (clades)
  14. 14 Separate introductions in NY and NJ, 2017
  15. 15 Transmission of pan-resistant and echinocandin-resistant C. auris, Texas and District of Columbia, 2021
  16. 16 Texas and DC clusters
  17. 17 Genomic data supports simultaneous and independent emergence of TX and DC clusters
  18. 18 Texas ech-r and pan-r strains cluster separately from ech-susceptible strains
  19. 19 Pathogen Genomics Centers of Excellence
  20. 20 Molecular Epidemiology Fellowship (MEF)

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