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Esophageal Cancer Outline
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Classroom Contents
Modern Radiation Therapy Techniques in the Treatment of Esophageal Cancer - Ann C. Raldow, MD, MPH
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- 1 Intro
- 2 Disclosures
- 3 Esophageal Cancer Outline
- 4 Epidemiology
- 5 Risk Factors
- 6 Anatomy
- 7 Clinical Presentation
- 8 Workup
- 9 Treatment Paradigm
- 10 What is Radiation Therapy?
- 11 How Does Radiation Kill Cancer Cells?
- 12 Impact of DNA Damage
- 13 How do the normal cells survive?
- 14 Fractionation
- 15 External Beam Radiation Therapy
- 16 Simulation
- 17 Dose Constraints
- 18 Esophageal Cancer Timeline
- 19 Van Hagen, CROSS
- 20 A Randomized Phase III Trial on the Role of Esophagectomy in Complete Responders to Preoperative Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESOPRESSO) (Park, Anticancer Res. 2019)
- 21 ESOPRESSO (Park, Anticancer Res. 2019)
- 22 Disease-free survival, progression-free survival, time to progression, and overall survival according to treatment arm
- 23 A multi-center, randomized, prospective study evaluating the optimal radiation dose of definitive concurrent chemoradiation for inoperable esophageal squamous cell carcinoma (Xu, ASCO 2018)
- 24 A randomized controlled phase Ill multicenter study on dose escalation in definitive chemoradiation for patients with locally advanced esophageal cancer: ARTDECO study (Hulshof, GIASCO 2020)
- 25 Conclusion
