Completed
It can be shown that a very large fraction of recombination events cannot be detected even with infinite mutation rate.
Class Central Classrooms beta
YouTube videos curated by Class Central.
Classroom Contents
Introduction to the Coalescent Theory - Lecture 2
Automatically move to the next video in the Classroom when playback concludes
- 1 Third Bangalore School on Population Genetics and Evolution
- 2 Introduction to the coalescent theory
- 3 The coalescent variance
- 4 The coa Review variance
- 5 Robustness of the coalescent
- 6 Example
- 7 Population genetics in and of itself only allows limited inference
- 8 Effective population size
- 9 Variable population size
- 10 In a constant population:
- 11 Exponential growth
- 12 Rule of thumb
- 13 Population structure
- 14 The structured Wright-Fisher model
- 15 This model can equally well be studied backward in time.
- 16 The two-deme model
- 17 Slow migration
- 18 Consequences of slow migration
- 19 Fast migration
- 20 Let 7; be the stationary probability that a lineage is in patch i.
- 21 Source-sink environments
- 22 Is the island model a good model?
- 23 Sex
- 24 Hermaphrodites and self-fertilization
- 25 Males and females
- 26 Stage structure
- 27 Stochastic demography
- 28 Why recombination?
- 29 Recombination backwards in time!
- 30 Recombination makes it possible for linked sites to
- 31 In the The ancestral recombination graph
- 32 In the limit as N - co:
- 33 A walk through tree space
- 34 Simulating data
- 35 How common is recombination?
- 36 Detecting recombination
- 37 It can be shown that a very large fraction of recombination events cannot be detected even with infinite mutation rate.
- 38 Overcoming the evolutionary variance
- 39 The number of SNPs in 20 copies of 10 kb, 1000 runs:
- 40 Same thing, with recombination:
- 41 Linkage disequilibrium LD
- 42 Why "linkage disequilbrium"?
- 43 Where does come from?
- 44 Assuming random mating, we have:
- 45 How does evolve? Well,
- 46 Decay of haplotype sharing
- 47 HapMap Project