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- Use of ROH to detect genomic regions with recessive disorders
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Classroom Contents
Genomic Inbreeding - Introduction to Genomics Theory
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- 1 - Summary from previous lectures
- 2 - What is inbreeding?
- 3 - Identity by descent and by state IBD vs IBS
- 4 - Consequences and measurement of inbreeding
- 5 - Runs of homozygosity ROH
- 6 - Comparison of pedigree vs ROH inbreeding in half-sib mating
- 7 - Calculation of genomic inbreeding coefficient based on ROH
- 8 - Lenth of ROH and the distance to the common ancestor
- 9 - ROH islands selection signature
- 10 - Use of ROH to detect genomic regions with recessive disorders
- 11 - Summary of the lecture
