From Experiments to Digital Twins: Advanced Process Modeling in Biopharmaceutical Development

From Experiments to Digital Twins: Advanced Process Modeling in Biopharmaceutical Development

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TFF flux prediction

12 of 16

12 of 16

TFF flux prediction

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From Experiments to Digital Twins: Advanced Process Modeling in Biopharmaceutical Development

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  1. 1 Intro
  2. 2 What do we need for better bioprocesses?
  3. 3 Circle of process modeling
  4. 4 Hybrid Modeling (high level view)
  5. 5 Why is Hybrid Modeling superior?
  6. 6 Model-based process optimization
  7. 7 Fast process characterization (iDOE)
  8. 8 Fast characterization with iDoE
  9. 9 Scale-up Modeling
  10. 10 Soft sensor
  11. 11 Ideal TFF Process conditions
  12. 12 TFF flux prediction
  13. 13 Continuous TFF prediction
  14. 14 Diafiltration (Test Data)
  15. 15 Summary
  16. 16 Hybrid Modeling Toolbox Demonstration

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