Delivering Fast, Flexible Next-Generation Sequencing through Innovations in Chemistry and Engineering

Delivering Fast, Flexible Next-Generation Sequencing through Innovations in Chemistry and Engineering

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ALIGNMENT AND COVERAGE METRICS

11 of 13

11 of 13

ALIGNMENT AND COVERAGE METRICS

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Delivering Fast, Flexible Next-Generation Sequencing through Innovations in Chemistry and Engineering

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  1. 1 Intro
  2. 2 SEQUENCING AND BATCHING ARE KEY CONTRIBUTORS TO LONG TURNAROUND FOR RESEARCH AND CLINICAL SEQUENCING
  3. 3 GREAT VARIATION IN REQUIRED TURNAROUND FOR CLINICAL AND RESEARCH APPLICATIONS
  4. 4 OPTICAL ENSEMBLE SEQUENCING BY SYNTHESIS VIA FLUORESCENTLY LABELED REVERSIBLE TERMINATED NUCLEOTIDES
  5. 5 RAPID NUCLEOTIDE INCORPORATION, IMAGING AND CLEAVAGE
  6. 6 HIGH PERFORMANCE COMPUTING REQUIRED FOR RAPID IMAGE PROCESSING, BASECALLING AND INTERPRETATION
  7. 7 A COMBINATION OF GPU AND CPU PROCESSING DELIVERS SPEED & VERSATILITY
  8. 8 HIGH TECHNICAL REPRODUCIBILITY
  9. 9 HIGH CORRELATION WITH ILLUMINA NEXTSEQ™ 2000
  10. 10 SEQUENCING QUALITY METRICS
  11. 11 ALIGNMENT AND COVERAGE METRICS
  12. 12 READ ACCURACY AND ERROR MODES
  13. 13 ACCURACY ACROSS CHALLENGING GENOMIC FEATURES

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