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Modeling uncertainty in parameters • One-way sensitivity analyses - Parameters have specified range and distribution of estimates - Model is run using extreme estimates for each parameter leaving all
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Cost and Coverage in Genomic Testing Medicine - Economic Perspectives
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- 1 Intro
- 2 Which outcomes or types of evidence matter? May vary by stakeholder type
- 3 Economic evaluation methods . Cost-effectiveness analysis (CEA)
- 4 Which economic evaluation method to use? • Payers may prefer budgetary impact analysis
- 5 What is a QALY? . Summary measure of population health
- 6 Cost-effectiveness . How to assess cost-effectiveness or cost savings - Comparison of two strategies
- 7 Modeling uncertainty in parameters • One-way sensitivity analyses - Parameters have specified range and distribution of estimates - Model is run using extreme estimates for each parameter leaving all
- 8 Medicare coverage of genomic tests and counseling . Genetic testing and counseling can be paid by Medicare for persons with certain diseases, based on medical necessity
- 9 Medicare and genetic testing for hereditary cancers: hereditary breast and ovarian cancer
- 10 Is genetic testing for hereditary cancers cost-effective? • Tumor testing for Lynch syndrome - In newly diagnosed patients with colorectal cancer (CRC) followed by
