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CBC RISK in BRCA MUTATION CARRIERS-META-ANALYSIS of 20 STUDIES
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Clinical and Genetic Determinants of Contralateral Breast Cancer - Webinar - Ambry Genetics
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- 1 Intro
- 2 Disclosures
- 3 OBJECTIVES
- 4 Why is it Important to Know About CBC?
- 5 Treatment Preference
- 6 Increase in Bilateral Mastectomy Rates
- 7 Bilateral Mastectomy Rates are Age Dependent
- 8 Overall Surgery Trends for Stage 1-1 Breast Cancer Patients
- 9 Risk Factors for CBC
- 10 CBC Risk-Clinical Trials
- 11 Decreasing CBC with Anti-Estrogen Treatment (ER+ Tumors)
- 12 RISK OF CBC and RADIATION THERAPY FOR BREAST CANCER
- 13 CBC Risk and Family History Ten Year Cumulative Risks
- 14 CBC RISK in BRCA MUTATION CARRIERS-META-ANALYSIS of 20 STUDIES
- 15 CBC risk for Non-BRCA Genes
- 16 Prevalence of Genetic Mutations 2012-2015
- 17 Prevalence of Genetic Mutations by Race/Ethnicity
- 18 Conclusions
- 19 Manchester Guidelines
- 20 CBC Prediction Models
- 21 Clinical Application-CBC Prediction
- 22 CBC and Survival
- 23 Association of CPM with Reduction in Mortality Selection Bias Stage
- 24 BRCA carriers and Survival with Bilateral Mastectomy
- 25 Why Patients Choose CPM
- 26 THANK YOU