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Classroom Contents
Challenges and Opportunities at the Nexus of Synthetic Biology, Machine Learning, and Automation
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- 1 Intro
- 2 Microelectronics vs. Biotechnology
- 3 What is Synthetic Biology?
- 4 Automated Protein Engineering: Fully Automated & HT Synthesis of TALENS
- 5 Preventing Transmission of Mitochondrial Diseases
- 6 Lycopene Pathway as a Test Case
- 7 Automated Cellular Engineering: east strain development via RNAi-assisted Genome Evolution
- 8 DOE Center for Advanced Bioenergy & Bioproducts Innovation
- 9 Vision: Develop an Automated Cellular Engineering (ACE) Platform
- 10 Multi-functional Genome-wide CRISPR System (MAGIC)
- 11 3. CRISPR/HDR Assisted Genome- scale Engineering (CHANGE)
- 12 Editing Efficiencies and Validation of CHANGE
- 13 Genome Editing with Single Nucleotide Precision
- 14 Three Main Types of Catalysis
- 15 Biocatalysis vs. Chemical Catalysis I
- 16 Combining Biocatalysis and Chemical Catalysis
- 17 Enzymatic Reduction of E/Z Olefins
- 18 Concept: Isomerization and Reduction
- 19 Tandem vs Sequential
- 20 Proposed Mechanism
- 21 Condition Optimization
- 22 Substrate Scope
- 23 Molecule Maker Lab Institute (an NSF AI Research Institute)
- 24 Summary
