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Ultimate goal: functional tests for sexually antagonistic fitness effects with CRISPR
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Classroom Contents
How and Why Do Sex Chromosomes Evolve?
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- 1 Intro
- 2 Sex chromosome conservation
- 3 Sex chromosome diversity
- 4 Sex chromosome evolution: model
- 5 Sex chromosome evolution: data
- 6 Sex chromosome evolution system
- 7 Threespine stickleback Y assembly timeline
- 8 Threespine stickleback Y assembly!
- 9 Three evolutionary strata are consistent with known inversions between X and Y
- 10 Testis-biased expression of genes that translocated or duplicated on the Y
- 11 Amhy is the candidate sex determination gene in threespine stickleback
- 12 Convergence and divergence in sex chromosome evolution
- 13 The Stickle Sex Chromosome Team
- 14 Quartet strategy to sequence neo-X and neo-Y chromosomes
- 15 Differentiation without substantial degeneration on Japan Sea neo-Y
- 16 Differentiation without substantial degeneration on blackspotted neo-Y
- 17 Gene tree approach to determine whether sex chromosomes are homologous
- 18 Different evolutionary trajectories of homologous Y chromosomes
- 19 Evolution of Gasterosteus sex chromosomes
- 20 Sex chromosome evolution: questions
- 21 Japanese species pair
- 22 Asymmetric reproductive isolation
- 23 Dorsal pricking and dorsal spine length map to the neo-X
- 24 Searching for signatures of sexually antagonistic selection on Japan Sea neo-Y
- 25 Four candidate peaks in genes associated with psychiatric disorders in humans
- 26 Ultimate goal: functional tests for sexually antagonistic fitness effects with CRISPR
- 27 Final thoughts
