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Phylogeny from DNA Sequences
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Can Evolution Be Understood Quantitatively? by Daniel Fisher
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- 1 DATE :06 March 2018, 16:00 to
- 2 Introduction
- 3 Can evolution be understood quantitatively?
- 4 Basic Laws of Evolution
- 5 Source of New Heritable Variation
- 6 Evidence for Evolution
- 7 Phylogeny
- 8 DNA Sequencing
- 9 Phylogeny from DNA Sequences
- 10 Basic Laws =Anything Can Evolve. But How Fast?
- 11 Who Cares About Quantitative Understanding?
- 12 Dynamics: What Determines Rate of Evolution?
- 13 Evolution & Population Size
- 14 Questions and puzzles
- 15 Difficulties
- 16 Learn to Love Bacteria & other microbes
- 17 Bacteria and Colossal Numbers
- 18 Large Populations and Rare Events
- 19 Can One Ever Predict Rate of Real Evolution?
- 20 Simplest "Toy" Landscape: Fitness Staircase
- 21 Ascending fitness staircase
- 22 Large populations: =many mutations each generation
- 23 Quantitative Experiment: Speed of Asexual Evolution
- 24 Connection to nature?
- 25 Simple evolution experiment:
- 26 Evolutionary-Ecological Dynamics
- 27 Comprehensive Bacterial & Ecological Evolution
- 28 Evolutionary-Ecological Dynamics Population of Organisms
- 29 Simplifying complex biology?
- 30 Toy models: "high-dimensional" Key caricature: approximate complexities by randomness
- 31 Fitness "snowscape" model
- 32 Sexual Evolution: Why Is Sex So Popular? Costs of sex:
- 33 Bacterial have only occasional sex Lateral gene transfer rate R per
- 34 Microbial Evolutionary Dynamics: Future Prospects Natural:
- 35 Make Evolutionary Biology Like Condensed Matter Physics - Experimental:
- 36 Laboratory evolution: Select for aggregation of yeast cells
- 37 Evolve: multicellular yeast reproduce by fragmentation
- 38 Q&A
