Building a Unified Cancer Immunotherapy Data Library

Building a Unified Cancer Immunotherapy Data Library

Strange Loop Conference via YouTube Direct link

Intro

1 of 30

1 of 30

Intro

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Classroom Contents

Building a Unified Cancer Immunotherapy Data Library

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  1. 1 Intro
  2. 2 CANDEL: The CANcer Data & Evidence Library
  3. 3 The Parker Institute Network
  4. 4 History of Cancer Treatment
  5. 5 Types Of Immunotherapy
  6. 6 What does the data scientist's job look like?
  7. 7 Physically and conceptually fragmented data
  8. 8 Design requirements
  9. 9 Talk outline
  10. 10 Datomic: Getting the Data Right
  11. 11 Datomic: Getting More Realistic
  12. 12 Better Aspects of Both Worlds
  13. 13 Getting Data into Datomic
  14. 14 Metamodel (Schema Annotations as Data)
  15. 15 Config Structure Derived from Metamodel and Schema
  16. 16 Import Validation
  17. 17 pret Command Line Workflow
  18. 18 The CANDEL Schema
  19. 19 The PRINCE clinical trial in Pancreatic Cancer
  20. 20 Importing the PRINCE dataset into CANDEL with pret
  21. 21 Steps of a data import
  22. 22 The end result of data import
  23. 23 Datomic Query via R: Tool Support
  24. 24 Datomic Query in Raw EDN
  25. 25 Spec Parser for Datalog over Plain JSON
  26. 26 Query Comparison
  27. 27 Enabling downstream applications
  28. 28 Plotting and standard analyses enabled by CANDEL
  29. 29 Circulating Tumor DNA: Mutant KRAS
  30. 30 CANDEL enables faster progress in cancer immunotherapy research

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