Integrating AI and Machine Learning in Life Sciences - Allen School Colloquia

Integrating AI and Machine Learning in Life Sciences - Allen School Colloquia

Paul G. Allen School via YouTube Direct link

Bringing Interpretable Models to Cancer Precision Medicine

27 of 35

27 of 35

Bringing Interpretable Models to Cancer Precision Medicine

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Classroom Contents

Integrating AI and Machine Learning in Life Sciences - Allen School Colloquia

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  1. 1 Intro
  2. 2 Al for Bio-Medical Sciences (AIMS) Lab
  3. 3 Overview
  4. 4 Published Al models detect COVID-19 in chest X-rays
  5. 5 What was the training data for these published models?
  6. 6 How can we test how robust the models are?
  7. 7 How robust are the models?
  8. 8 What is important for the model's predictions?
  9. 9 Can we fix shortcut learning with improved data?
  10. 10 Conclusions
  11. 11 Acknowledgements
  12. 12 Outline
  13. 13 Explainable AI
  14. 14 Examples
  15. 15 Intuition
  16. 16 The recipe
  17. 17 Unified framework
  18. 18 SHAP's ingredients
  19. 19 Human-friendly
  20. 20 Game-theoretic
  21. 21 Information-theoretic
  22. 22 Choosing optimal combinations is hard
  23. 23 This is the perfect opportunity for predictive models
  24. 24 In high stakes scenarios, models should be interpretable
  25. 25 A simple fix: ensemble attributions
  26. 26 Interpretability uncovers transcriptional programs
  27. 27 Bringing Interpretable Models to Cancer Precision Medicine
  28. 28 Contrastive Analysis
  29. 29 Latent Variable Models
  30. 30 VAE Model
  31. 31 Problem
  32. 32 Contrastive Latent Variable Model
  33. 33 Background datasets
  34. 34 Contrastive VAE
  35. 35 Inspecting the salient latent values

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