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Case Example: Mutation-Treatment Interactions
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AI for Clinical Trials and Precision Medicine - Ruishan Liu
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- 1 Intro
- 2 Al for Medicine
- 3 Al for Clinical Trials
- 4 Strict Eligibility is a Barrier to Trial Enrollment
- 5 How Clinical Trial Eligibility Criteria are Decided?
- 6 Trial Pathfinder
- 7 Shapley Analysis
- 8 Data-driven criteria enlarges pool of eligible patients while reducing HR
- 9 Relaxing threshold
- 10 Piloted by Roche to Guide Cancer Trial Design
- 11 Precision Medicine for Oncology
- 12 Implementation on real-world clinico-genomics data
- 13 Case Example: Mutation-Treatment Interactions
- 14 Systematic pan-cancer analysis of mutation-treatment interactions
