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What Role Does Brown Fat Play in Human Health and Disease?
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Classroom Contents
A Burning Question - Can Some Body Fat Keep You Thin?
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- 1 THE ROCKEFELLER UNIVERSITY
- 2 Obesity Threatens Public Health
- 3 Clinical Case
- 4 Obesity Is Defined by Excess Fat (Adipose Tissue)
- 5 Why Do We Need Adipose Tissue?
- 6 White Adipocytes (Fat Cells)
- 7 Is Fat the Problem or Could It Be Part of the Solution?
- 8 Metabolic Futile Cycle Generates Heat
- 9 Brown Fat Protects Newborns from Hypothermia
- 10 Inducible Brown Fat Can Help Adult Animals Survive in the Cold
- 11 PRDM16 Controls Brown Fat Development
- 12 3D View of Thermogenic Fat
- 13 Physiological Effects of Thermogenic Fat
- 14 Targeting Thermogenic Fat to Treat Obesity and Comorbid Diseases
- 15 Conventional Notions Suggest This Will Not Work
- 16 Cold-Inducible Brown Fat in Adult Humans
- 17 What Role Does Brown Fat Play in Human Health and Disease?
- 18 Variables Associated with Brown Fat
- 19 Brown Fat and Cardiometabolic Health
- 20 Brown Fat Protects Against Sequelae of Obesity
- 21 What Explains the Benefits Associated with Brown Fat?
- 22 The Possibility of Brown Fat Activating Therapies
- 23 A Cautionary Tale
- 24 Current Therapeutic Targets
- 25 What Determines Brown Fat Activity ?
- 26 Can We Identify Genetic Variants That Control Brown Fat?
- 27 Summary
