Bioinformatics Capstone: Big Data in Biology

Overview

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In this course, you will learn how to use the BaseSpace cloud platform developed by Illumina (our industry partner) to apply several standard bioinformatics software approaches to real biological data. In particular, in a series of Application Challenges will see how genome assembly can be used to track the source of a food poisoning outbreak, how RNA-Sequencing can help us analyze gene expression data on the tissue level, and compare the pros and cons of whole genome vs. whole exome sequencing for finding potentially harmful mutations in a human sample. Plus, hacker track students will have the option to build their own genome assembler and apply it to real data!

Syllabus

Assembly and Annotation of the SARS-CoV-2 Genome
Variant Detection and Classification of SARS-CoV-2
SARS-CoV-2 Spike Protein Structure Analysis

Taught by

Phillip Compeau and Pavel Pevzner

Reviews

1.5 rating, based on 2 Class Central reviews

3.7 rating at Coursera based on 27 ratings

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Anonymous

There's a significant delay in grading time. Could you please assist in identifying ways to improve the efficiency of the grading process? Your help would be greatly appreciated. Thank you!
Paolo Binetti

This course, as others in Coursera catalog, suffer from Coursera's new learning policies, which deteriorate the learnang experience, significantly slowing progress towards completion. In particular I refer to their decision NOT to give you full acce…

This course, as others in Coursera catalog, suffer from Coursera's new learning policies, which deteriorate the learnang experience, significantly slowing progress towards completion. In particular I refer to their decision NOT to give you full access to course content during the subscription period. This happens if you are too early or too late in what they call a "session". Since this and their other courses are essentially unmanned, such limitation is totally needless. So, for example, I have completed the peer-reviewed assignment of week 1 late, and was forced to "switch sessions" to continue. But the next session being in one month, I cannot access the peer-reviewed course material of week 2 for a whole month! Because each week's study is designed to be covered in ... well, a week, and not a month, this is is nonsense.

Technical support replied that this is their policy and they have no power to change it, in spite of escalating to one management level.

Be aware of this hassle if you decide to take this and other Coursera courses.

Taught by

Tags

Algorithms and Data Structures Capstone

Hacking COVID-19 — Course 1: Identifying a Deadly Pathogen

Genome Sequencing (Bioinformatics II)

Bioinformatics

Comparing Genes, Proteins, and Genomes (Bioinformatics III)

Analyze Your Genome!

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