Organic Chemistry in Biology and Drug Development

Organic Chemistry in Biology and Drug Development

IIT Kharagpur July 2018 via YouTube Direct link

Lecture-63 : QSAR principles

64 of 64

64 of 64

Lecture-63 : QSAR principles

Class Central Classrooms beta

YouTube videos curated by Class Central.

Classroom Contents

Organic Chemistry in Biology and Drug Development

Automatically move to the next video in the Classroom when playback concludes

  1. 1 Organic Chemistry in Biology and Drug Development
  2. 2 Lecture 1 : A brief introduction to Molecules of Life
  3. 3 Lecture 2 : Biological Macro molecules and Small molecules: Importance and functions
  4. 4 Lecture 3 : Amino Acids: The building block of proteins
  5. 5 Lecture 4 : Amino acids: separation and detection, Electrophoresis and Ninhydrin reaction
  6. 6 Lecture 5 : Method of determination of Amino acid sequence: primary structure of polypeptide/protein
  7. 7 Lecture 6 : Selective peptide bond cleavage: Enzymatic and Non-enzymatic methods
  8. 8 Lecture 7 : Peptide synthesis: Protecting groups for amine and carboxyl functionality
  9. 9 Lecture 8 : Peptide synthesis (continued): Protection, coupling and deprotection methods
  10. 10 Lecture 9 : Recent development of coupling agents;
  11. 11 Lecture 10 : Hierarchial structure of proteins: Secondary, tertiary and quaternary structure
  12. 12 Lecture 11 : Ramachandran plot and protein purification techniques
  13. 13 Lecture 12 : Protein Purification Techniques (Contd.)
  14. 14 Lecture 13 : Introduction to Enzymes and its kinetics
  15. 15 Lecture 14 : Enzyme catalysed reactions and introduction to catalytic activity of proteases
  16. 16 Lecture 15 : Enzyme Kinetics (Contd.)
  17. 17 Lecture 16 : Concept of Enzyme Inhibition
  18. 18 Lecture 17 : Concept of Enzyme Inhibition (Contd.)
  19. 19 Lecture 18 : Problems on Enzyme Kinetics and Enzyme Inhibition
  20. 20 Lecture 19 : Synthetic Biology
  21. 21 Lecture 20 : Synthetic Biology (Contd.)
  22. 22 Lecture 21 : Synthetic Biology (Contd.)
  23. 23 Lecture 22 : Nucleic Acid
  24. 24 Lecture 23 : Nucleic Acid (Contd.)
  25. 25 Lecture 24 : DNA sequencing method
  26. 26 Lecture 25 : DNA sequencing method (Contd.)
  27. 27 Lecture 26 : DNA sequencing method (Contd.)
  28. 28 Lecture 27 : Synthesis of oligonucleotide
  29. 29 Lecture 28 : Central dogma: DNA replication, transcription and translation
  30. 30 Lecture 29 : Central dogma: DNA replication, transcription and translation (Contd.)
  31. 31 Lecture 30 : Central dogma: DNA replication, transcription and translation (Contd.)
  32. 32 Lecture 31 : Central dogma: DNA replication, transcription and translation ((Contd.)
  33. 33 Lecture 32 : Central dogma: DNA replication, transcription and translation (Contd.)
  34. 34 Lecture 33 : Molecular Biology
  35. 35 Lecture 34 : Molecular Biology (Contd.)
  36. 36 Lecture 35 : Chemistry of cofactors/coenzymes
  37. 37 Lecture 36 : Chemistry of cofactors/coenzymes (Contd.)
  38. 38 Lecture 37 : Chemistry of cofactors/coenzymes (Contd.)
  39. 39 Lecture 38 : Chemistry of cofactors/coenzymes (Contd.)
  40. 40 Lecture 39 : Chemistry of cofactors/coenzymes (Contd.)
  41. 41 Lecture 40 : Chemistry of cofactors/coenzymes (Contd.)
  42. 42 Lecture-41: " Introduction to Drug Discovery Process"
  43. 43 Lecture-42: " Fundamental Principles of Drug Development Process"
  44. 44 Lecture-43: " Combinatorial chemistry"
  45. 45 Lecture-44: "Neurotransmitters"
  46. 46 Lecture-45: " Catechol amine based and GABA neurotransmitters"
  47. 47 Lecture-46: " Hypertension: humoral mechanism and renin/angiotensin system"
  48. 48 Lecture-47: " Inhibitor design of angiotensin converting enzyme"
  49. 49 Lecture 48: Antimicrobial drugs
  50. 50 Lecture 49: Chemistry of penicillins
  51. 51 Lecture 50: Resistance to beta-lactam antibiotics
  52. 52 Lecture 51: Mechanistic studies of beta-lactamase
  53. 53 Lecture 52: Non beta-lactam antibiotics
  54. 54 Lecture 53: Mechanistic enzymology of Isopenicillin N synthase
  55. 55 Lecture-54 : Polyketide Biosynthesis
  56. 56 Lecture 55 : Biosynthesis of macrolide polyketides and introduction to virus
  57. 57 Lecture 56 : Anti-viral drugs
  58. 58 Lecture-57 : Cancer and Chemotherapy
  59. 59 Lecture-58 : Anti-cancer drugs (contd)
  60. 60 Lecture 59 : Aromatase inhibition and Anti-ulcer drugs
  61. 61 Lecture-60 : Cholesterol lowering agents
  62. 62 Lecture 61 : Cholesterol Biosynthesis
  63. 63 Lecture-62 : Pharmakinetics and pharmadynamics
  64. 64 Lecture-63 : QSAR principles

Never Stop Learning.

Get personalized course recommendations, track subjects and courses with reminders, and more.

Someone learning on their laptop while sitting on the floor.