Broad Institute Courses

Multi-omics Variational Autoencoding - Deep Dive and Primer

Explore multi-omics variational autoencoding for integrating complex biological datasets. Learn about MOVE pipeline, data preprocessing, model optimization, and approaches for determining associations between omics variables and categorical labels.

• YouTube
• 1 hour 32 minutes
• On-Demand
• Free Video

Germline Variation and CRISPR Screens - MPG Primer 2023

Explore germline variation and CRISPR screens in this comprehensive primer. Gain insights into complex trait genetics, human genetic variation, and cutting-edge DNA sequencing methods.

• YouTube
• 38 minutes
• On-Demand
• Free Video

Protein Design Using Deep Learning

Dive into protein design using deep learning with David Baker. Explore cutting-edge techniques and insights at the intersection of AI and biomedical research.

• YouTube
• 52 minutes
• On-Demand
• Free Video

How Cells Divide Labor Using Communication and Spatial Cues - 2023

Explore how cells divide labor through communication and spatial cues, focusing on intestinal enterocytes and fibroblasts. Gain insights into tissue organization and gene expression patterns.

• YouTube
• 33 minutes
• On-Demand
• Free Video

AI in Radiology: Pattern Detection, Fairness, and Clinical Applications - Lecture Series

Explore AI's ability to detect hidden patterns in X-ray images and its implications for radiologists. Delve into fairness considerations in chest X-ray diagnosis models and their potential impacts on clinical practice.

• YouTube
• 1 hour 34 minutes
• On-Demand
• Free Video

Accelerating Rare Disease Research: Patients as Partners - Rare Disease Day 2023

Explore cutting-edge research and patient partnerships in rare diseases. Gain insights from experts on mitochondrial disorders, gene therapies, and collaborative initiatives to accelerate progress in this critical field.

• YouTube
• 2 hours 46 minutes
• On-Demand
• Free Video

Stochasticity in Transcription - MPG Primer 2023

Dive into stochasticity in transcription, exploring single-cell data, dynamic regulatory elements, and transcriptional bursting in autoimmune diseases. Gain insights into modeling techniques and gene regulatory programs.

• YouTube
• 50 minutes
• On-Demand
• Free Video

Machine Learning about Sudden Cardiac Death from ECG Waveforms

Explore machine learning applications in predicting sudden cardiac death using ECG waveforms. Gain insights into innovative approaches combining AI and biomedical research for critical healthcare advancements.

• YouTube
• 1 hour 9 minutes
• On-Demand
• Free Video

Base Editing and Prime Editing: Precise Genome Modification Without DNA Breaks

Explore groundbreaking gene editing technologies: base editing and prime editing. Discover their therapeutic applications and advancements in precision DNA modification without double-strand breaks.

• YouTube
• 1 hour 10 minutes
• On-Demand
• Free Video

Pharmacological Adaptation of Proteostasis to Ameliorate Aging-associated Degenerative Diseases - 2023

Explore proteostasis adaptation for aging-related diseases. Discover kinetic stabilizers, lysosomal flux enhancers, and autophagy activators as potential treatments for amyloidosis and neurodegenerative disorders.

• YouTube
• 58 minutes
• On-Demand
• Free Video

RNA Modifications and Their Impact on Biological Regulation - Broad-MIT Seminar 2023

Delve into post-transcriptional RNA modifications, focusing on m6A methylation and demethylation. Explore their impact on biological regulation, mammalian development, and plant growth, with insights into new chemical sequencing methods.

• YouTube
• 1 hour 11 minutes
• On-Demand
• Free Video

Cross-cohort Analysis via Cloud Genomics - MPG Primer

Dive into cross-cohort analysis using cloud genomics, exploring trusted research environments, methodologies, and tools for efficient genetic data processing and interpretation.

• YouTube
• 46 minutes
• On-Demand
• Free Video

Computational Protein Design and De Novo Design of Proteins

Explore computational approaches for designing functional proteins, including surface pattern analysis and de novo topology exploration, with applications in vaccine design, T-cell therapies, and biosensors.

• YouTube
• 1 hour 35 minutes
• On-Demand
• Free Video

High-Throughput In Silico Genetic Screen for 3D Genome Organization - Models, Inference and Algorithms

Explore cutting-edge approaches in 3D genome organization research, including in silico genetic screening and graph representation learning for analyzing multiscale chromatin structure.

• YouTube
• 1 hour 50 minutes
• On-Demand
• Free Video

Single-Cell Spatiotemporal Modeling - From RNA Velocity to Spatial Transcriptomics

Explore single-cell spatiotemporal modeling with dynamo framework and Stereo-seq technology. Uncover insights into cellular states, transitions, and spatial dynamics in developmental biology and neuroscience.

• YouTube
• 52 minutes
• On-Demand
• Free Video