Quantifying the Evolutionary Advantage of Recombination in Finite Populations

Explore a 42-minute lecture by Denis Roze from CNRS on the evolutionary advantages of recombination in finite populations. Delve into recent analytical and simulation results that quantify the strength of selection for recombination along continuous chromosomes in finite, diploid populations. Discover how selection for recombination caused by recurrent deleterious mutations can often be approximated using a simple function of effective population size, chromosomal mutation rate, and genetic map length. Examine the extension of these findings to partially inbred populations and the effect of transposable elements on eukaryotic genomes. Gain insights into one of the most widely cited hypotheses explaining the evolutionary maintenance of sex and recombination, which posits that recombination enhances natural selection efficiency by reducing interference among selected loci.