This course is a journey into the biology of the human genome and will highlight the scientific, social, and personal perspectives of people living with a variety of traits.
Overview
Syllabus
- Origin of mutation/variation
- Types of mutations and various causes of mutation.,Allelic frequency, and the spread of alleles in a population.
- How to obtain and interpret personal genetic information
- Personalized genetics: sample acquisition, DNA extraction and processing.,Interpretation of results.
- Simple genetic traits
- Molecular causes of monogenic traits.,Loss-of-function vs. gain-of-function alleles, and dominance.
- Multifactorial traits
- Polygenic traits, qualitative and quantitative measures.,Twin studies, relative risk, and genome-wide association studies (GWAS).
- Pharmacogenetics: genes and drugs
- Pharmacokinetics and pharmacodynamics.,Alleles affecting drug metabolism.,Personalized medicine.
- Origin of mutation/variation
- Types of mutations and various causes of mutation.,Allelic frequency, and the spread of alleles in a population.
- How to obtain and interpret personal genetic information
- Personalized genetics: sample acquisition, DNA extraction and processing.,Interpretation of results.
- Simple genetic traits
- Molecular causes of monogenic traits.,Loss-of-function vs. gain-of-function alleles, and dominance.
- Multifactorial traits
- Polygenic traits, qualitative and quantitative measures.,Twin studies, relative risk, and genome-wide association studies (GWAS).
- Pharmacogenetics: genes and drugs
- Pharmacokinetics and pharmacodynamics.,Alleles affecting drug metabolism.,Personalized medicine.
Taught by
Matthew Cook
Tags
Related Courses
Related articles
Reviews
4.7 rating, based on 7 Class Central reviews
-
Very well done and not too demanding course about basics of genetics, especially explained on human genome. Although it was well explained and easily understandable, some tasks demanded good focus and thinking twice. I would greatly recommend it as the first online course for studying genetics.
-
One of the best courses. Any category. It was so much fun. Yes, it has a "fun with flag vibe"... but is it a bad thing? It's awesome.
-
A fantastic introduction to genetics for beginners. If you've every struggled to understand the basics of genetics then this is the course for you. It was developed in collaboration with people at 23andMe, so a bonus is that you will be able to better understand the results of your personal genetics kit if you get one from 23andMe.
-
This course is a good introduction to various aspects of genetics, with an emphasis on understanding personal genotype data as presented by 23andme. The instructors have a very engaging style that actually takes advantage of the format instead of being a video of a talking head, as some courses still are.
-
ties to 23andme was a little bit distracting but I assumed that might be the case going into the study
-
-
